Sermorelin vs MK-677 what are key differences and which is better to get a lean body
Which has least side effects ?
Kaustav
I'd say cjc dac instead of sermorelin, with mk677 used to pulse gh at opportune times like at night or morning.
Also worth noting i think mk-677 works via ghrelin which can make you hungry af. Alternatively you can use a ghrp like ghrp2 or ipamorelin for the hgh spikes.
Mk-677 can make you sleepy, the injectable peptides ive tried dont seem to have quite as acute an effect.

So step 1: increase resting base gh secretion via a ghrh, ideally a long acting one like cjc dac
Step 2: Get the big natural gh pulses supported and strengthened, your normal gh pulses are already bigger but if you take mk677 before bed itll boost your natural nightly gh pulse a lot more. injectable ghrps can also be used, perhaps before workouts?
Nelson
Mk-677 is cheaper, oral instead of injectable, and effective for weight gain, not for leaning out as Sermorelin. But Mk 677 is not FDA approved.
Gene
I ran Sermorelin for almost 2 years with very good results. Leaned our even more and added more lean muscle mass. It's the only FDA approved GhRP. Research sites sell it cheap as well.
Jordan
I've read that mk 677 isn't suppressive to your natural gh production. Does anyone have experience with sermorelin to say the same is true or is sermorelin suppressive?
Gene
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191) is a GhRP just like Sermorelin. Like GhRP6 and GhRP2, all stimulate the ghrelin receptors on the pituitary gland and are a growth hormone secretagogue which mimics the growth hormone stimulating action of the endogenous hormone ghrelin...so in other words, they stimulate the pituitary to produce more endogenous GH...all are agonists not suppressors. As I noted here and on reddit, Sermorelin worked great for me but all of these GhRP's take time to work and where you will see real results. Plus, all of these need to be injected or taken each and every night before bed (sometimes more frequently) with no carbs in your bloodstream.

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