Selank / Semax
Tryptophan vs 5HTP, what is the difference and which is better?
Tryptophan V.S. 5HTP, what is the difference and which is better?
Tryptophan crosses the blood brain barrier much easier than 5-HTP, so it can be more effective at raising brain serotonin levels with less increase in systematic serotonin levels which is a good thing. Too much systematic serotonin can damage your heart.
You can take both. I also suggest combining them with vit-B6, vit-C and possibly EGCG if your stomach can handle it (tryptophan and 5htp should be taken on an empty stomach)
If L-Tryptophan works, then you should stick with that, as it's rate-limited (doesn't result in overproduction of serotonin) and can be stored by the body for future use.
5-HTP mainly existed and grew in popularity as the US government banned the sale of L-Tryptophan. As that ban has been lifted, you should start with L-Tryptophan.
It would make sense to use 5-HTP rather than L-Tryptophan if you have issues converting L-Tryptophan to 5-HTP or have absorption problems. Otherwise, 5-HTP can easily result in serotonin syndrome and isn't really suited for long-term used.
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