Adrafinil users please share your experience.
I find it interesting how some people do not immediately respond to this drug because sometimes it takes repeated exposures before the liver properly converts significant amounts of the compound to Modafinil. (Citation needed, but who needs that when you have Reddit comments.)
I am finally starting to respond to it after the 4th time dosing 500 mg. How many times did it take you guys?
The first time I dosed it, I noticed a mild increase in sociability (placebo?). Hardly anything the 2nd and 3rd time. This last time, however, I am starting to feel increased concentration and definite social confidence. I think caffeine puts it to shame in terms of wakefulness promotion, though. (Isn't this where Adrafinil is supposed to excel? Sigh.) Overall, it doesn't do too much for my physical brain fog feelings or anhedonia (fair enough). It is pretty good at promoting focus, though. I may be able to use it as a substitute for my Adderall when I enroll in grad school. Hopefully I'm not merely trading neurotoxicity for hepatotoxicity.
The owner of Ceretropic has hinted at developing an analogue of Modafinil which should curtail any liver OR legal risks, so I think I'll hold out before buying any more -afinil products.
I think I'm getting less of the pesky adrenergic/histaminergic side effects but it always makes me snotty for a day or two afterwards (I already have sinus issues so this is problematic and another reason to not use too often). It's perfect for hours of organizing/filing/paper stacking and cleaning and turns me into a tunnel-visioned writing freak which for a guy who gets paid by the word comes in handy on occasion.
I'm concerned about long term use. Hoping once a week isn't a lot especially at the dose I use. I DO NOT consider the -ifinil family nootropics. They are certainly productivity enhancers and cognitive boosters but then so is methylphenidate for that matter. Certainly doesn't mean that long term use (even long term occasional use) is necessarily a good idea.
The half life Adrafinil is reviewed to be about 15 hours. Meaning it will be "out of your system" in a little over three full days.
If you're taking it once a week you are still spending most of your time (four days out of seven) not under the influence. That would seem like a sustainable average for me, but always pay attention to how you feel. If it feels like you are building a tolerance or not getting what you used to out of it cut back.
Im in Canada and have gotten modafinil online which is a much better option. But it's not something your going to want to use consistently
Day 1 on Adrafinil: At 7AM I took 100mg of caffeine in the morning just to be able to wake up and get off bed. My husband has RLS and last night he was just kicking it. Ha. Sucker.
7:30AM I took 300mg of Adrafinil
8AM One cup of coffee. I did not need it, but I love the flavor. I was awake but foggy. Fully functional though.
9AM Bright awake. Happy. Moving, getting things done.
1PM Took another 300mg of Adrafinil. I did not feel I needed it, but since it takes longer to take effect I did not want to pass out on my desk or have micro sleeps.
2PM Lunch and half a can of Coke Zero.
3PM Bright awake. Moving, working, completing my tasks.
4:30PM Cup of coffee. I decided to have it Heck I should be in route to the gym and instead I am typing here, it's 7PM.
All day long I have been happy, moving, feeling productive, dancing while driving. I feel the same as when I was taking Modafinil; the only difference is that my mouth is watery and my teeth feel a little sensitive. My eyes feel dry, I wear contacts, but just as dry as Modafinil made them.
I have not had ANY micro sleeps! I was getting several micro sleeps and disoriented moments while on Nuvigil, 5hr energy and 5 cups of coffee a day.
On the other hand, my friend who I wanted to take modafinil tried it, and she noticed it at just 100 mg dose! she thought 50 would be right for her, but bad taste + toxicity meant she won't even try it again. She's inching closer to switching to modafinil from adderall though, (pill scrip from a doc though)
Today I restarted my test. As I mentioned previously, I don't have equipment that is precise enough to measure 150mg, so instead, I measured 300mg, dissolved it in one cup of carbonated water (Adrafinil is acid-soluble, but not water-soluble), and I drank a half-cup of the solution. It tasted vaguely like grapefruit juice.
I haven't noticed any negative effects. My daily Sudoku exercises went significantly faster than they have recently, but not nearly as fast as I was able to do them pre-injury. I don't think that proves anything other than today was a good day. Consistent results over three or more weeks constitutes meaningful results. One day doesn't say much.
The reason I'm testing Adrafinil is so I can maintain the necessary level of modafinil that my doctor prescribed, and that my own experience has verified is the minimum I can function with, after Medicare refused to pay for more than half the prescribed dose that I have depended on for several years.
Adrafinil is metallized into modafinil, and so it is essentially the same drug, however is considered to be less likely to be abused, because it is much slower acting. I'm taking my first dose of modafinil in the morning as I've always done, but now that medicare won't pay for the second half of my prescription, instead of taking my second dose of modafinil at noon, I'm taking it in the form of adrafinil in the morning, giving the slower acting form of the drug time to kick in at noon when I need it.
Thankfully, adrafinil is a well understood drug that had been in regular use world wide since the early 70's, and it is considered to be one of the safest stimulants. It does not require a prescription, and a one month supply costs $6.00 whereas the equivalent amount of modafinil would have cost somewhere in the range of $900.00 a month!
Root beer is not a good substitute for carbonated water. Adrafinil won't dissolve in it. I'm guessing the root beer releases too much of its carbonation, or possibly that the particles of adrafinil catalyze faster release of the carbonation. Whatever the reason, the root beer went flat after adding the adrafinil, and it happened instantly, with no noticeable foaming.
Some day I'll look into how that was possible, but the lesson for today is to stick with sugar-free Mountain Dew to dissolve adrafinil. I added vinegar to the root beer so the adrafinil would dissolve. It doesn't taste very good (understatement) but I immediately washed it down with more unadulterated root beer.
I also tried using a balance to measure the dose, but I couldn't get the needle to move when changing the balance weight less than 20mg, which meant I still have the same issue with the balance that I have with the digital scale. The scale lacks the precision necessary to measure a 150mg dose. Since the digital scale is easier to use, I measured 300mg (to the nearest 5mg) with the digital scale, and added it to a cup of liquid so I could measure half the liquid to get the appropriate 150mg dose (which the body metabolizes into 210 mg of Modafinil), which approximately matches the prescribed 200 mg of Modafinil that Medicare won't cover. (I actually measured 290mg, which after cutting the solution in half would result in the equivalent of a 203mg dose of Modafinil, but I did the calculation after the fact. At the time, I was just choosing to be satisfied with a quantity slightly under 300.)
The Adrafinil test is providing mixed results. Initially, the drug obviously works, and even appears to work better than Modafinil. It doesn't kick in nearly as quickly, but it seems to stay with me longer (which is opposite what I have read about it). When using Modafinil alone, my average time to complete a moderately difficult Sudoku puzzle is between 10 to 30 minutes, but on days when I have been taking the Adrafinil, my average time is less than six minutes. In addition, I find no need to write my "50% certain" notes in the squares, because it takes just about as long to reason out the uncertainty as it takes to write the notes. I'm also frequently seeing the solutions at a glance, rather than having to reason them out. On Modafinil, I often think I see solutions at a glance, but I end up having to erase my entries and start over, which is the difference between the puzzles that take ten minutes, and the ones that take 30 minutes. The Adrafinil works about the same as Modafinil in terms of allowing me to stay awake and focused, but I'm clearly more productive when taking the Adrafinil, which makes no sense, since Adrafinil is the same drug once metabolized.
Unfortunately, two trials in a row, I have gotten flu-like symptoms starting with an increasingly bad headache that has started both times on the 4th day of taking 150mg of Adrafinil. This affect might make sense if my body isn't getting rid of it as fast as it gets rid of Modafinil, but since Adrafinil is the same drug once it has been metabolized, there must be some other factor.
I'm not going to take the drug tomorrow morning, and when I try it for the last time, I'm going to cut the dose in half. If the drug seems to be working at that dose, then I'll continue with it, but I'm not going to continue testing it if I continue having negative side-effects. This next test will be my last. I'm also thinking I should talk with my doctor about scheduling blood tests for liver and kidney function soon.
I started my third and final test this morning, this time taking 75 mg of Adrafinil by dissolving 300 mg in 2 cups of diet Mountain Dew, and drinking a half-cup of the solution. It is my hope that at the reduced dose, the gradual accumulation versus gradual elimination of the drug will be equivalent to a 150 mg daily dose. Previously the drug worked better than expected, but unacceptable side-effects began on the fourth day of taking the drug. I am continuing to take half (200 mg) of my prescribed 400 mg dose of Modafinil. the other half of the 400 mg prescribed dose to be metabolized from the Adrafinil. Both drugs are considered very safe. Modafinil is a controlled substance. Adrafinil has been used by the US military and in other countries since the early 1970's and is also considered to be very safe, but with a potential risk of liver damage with long-term use at 300 mg daily. Since Medicare declined to pay for my 400 mg prescription, only agreeing to pay for half the dose, which I already know is inadequate as a treatment for symptoms of traumatic brain injury, adrafinil is my only legal recourse.
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