Selank / Semax
Choline bitartrate vs cdp choline vs alpha cdp: pros and cons?
Choline bitartrate .. Vs cdp choline.. Vs alpha cdp..
Whats pros and cons?
Rotate, anywhere from 4-8 weeks. I will sometimes throw in bitartrate or Lecithin on rotation to save money.
Choline bitartrate is useless. Bioavailability near zero. Citicholine or choline CDP.
A lot of people seem to get the best results from either CDP or Alpha GPC. That's why I tell people to buy a bottle of each and test for a few weeks. Roughly even numbers of people prefer one to the other and there is really no way to know which you are ahead of trying both.
Choline bitarate has some agitation/depressive symptoms that seems to occur much more often then with cdp... Cdp choline is also one of the most bioavailable forms
I take both alpha gpc and cdp choline because I'm told they work slightly different and there can be some benefit. I rarely get racetam headaches without but I do find the effect of choline + racetam greater than racetam alone. I've read on reddit that choline bitartrate is the least bioavailable version.
Well, in the fitness supplement industry gpc was like the Ferrari of choline forms.
Bitartrate and other cholin molecules like DMAE dont have the edge at nootropic purposes. I think its because they dont pass blood-brain-barrier or sth?
Well, "in" i guess.
Citicoline is my favorite and choline source of choice I use in Nootroo. It seems to work well for the greatest number of people, has positive stimulating effects, and has a lot more research than alpha-gpc.
Both increase acetylcholine in different ways. Not really sure how, but CDP-Choline is broken down to phosphatidylcholine, then acetylcholine.
Alpha-gpc results in higher acetylcholine concentrations per mg. Downside is that its really difficult to handle in powderform as its extremely hygroscopic. It absorbs the moisture in the surounding air very rapidly and turns into goop. Cdp-choline results in lower aCh levels than alpha gpc per mg but not by that much. A plus side is that one of the byproducts during metabolization is uridine which can be beneficial.
Also alpha gpc is mainly sold in 2 varieties. The 99% version which is extremely hygroscopic and the 50% which has added fructose to combat the hygroscopic effects. Keep in mind that if you go for the 50% version that you would have to double the dosage as it is half concentrated.
Also alpha gpc is mainly sold in 2 varieties see reddit. The 99% version which is extremely hygroscopic and the 50% which has added fructose to combat the hygroscopic effects. Keep in mind that if you go for the 50% version that you would have to double the dosage as it is half concentrated.
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